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服务
产品  
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Rabbit Anti-SIPA1L1 Antibody/抗信号诱导增殖相关蛋白1样蛋白1多抗
| 名称
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Rabbit Anti-SIPA1L1 Antibody
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| 中文名
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抗信号诱导增殖相关蛋白1样蛋白1多抗
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| 基本描述
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SIPA1L1 (Signal-induced proliferation associated-like protein 1) is a member of the SIPA1 family of RapGAPs. SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of -risk papillomaviruses. Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1. CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation.
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| 性 状
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Lyophilized or Liquid
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| 纯化方法
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affinity purified by Protein A or Protein G
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| 储 存 液
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0.01M PBS(pH7.4) with 1% BSA。
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| 存储条件
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Store at -20°C.
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| 亚型
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IgG
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