|
服务
产品 
|
A-779
| 名称
|
A-779
|
| 别名
|
|
| 序列(单字母缩写)
|
DRVYIH{D-Ala}
|
| 序列(三字母缩写)
|
{ASP}{ARG}{VAL}{TYR}{ILE}{HIS}{d-ALA}
|
| 基本描述
|
A-779 is a potent and selective Ang (1-7) antagonist. A-779 antagonizes several actions of Ang (1-7), including A-779's antidiurectic effect and the changes in MAP produced by Ang (1-7) microinjection into the dorsomedial or ventrolateral medulla.
|
| 分子量
|
873.000
|
| 化学式
|
C39H60N12O11
|
| 纯度
|
> 95%
|
| 存储条件
|
Store at -20°C.
|
| 注释
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
Santos RA, et al. Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension. May 2006; 47(5): 996-1002.
Iwata M, et al. Angiotensin-(1-7) binds to specific receptors on cardiac fibroblasts to initiate antifibrotic and antitrophic effects. Am J Physiol Heart Circ Physiol. Dec 2005; 289(6): H2356-H2363.
Gonzalez-Villalobos R, et al. Megalin binds and internalizes angiotensin-(1-7). Am J Physiol Renal Physiol. May 2006; 290(5): F1270-F1275.
|
|