| 名称
|
Calcitonin (8-32), Salmon
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| 别名
|
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| 序列（单字母缩写）
|
VLGKLSQELHKLQTYPRTNTGSGTP-NH2
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| 序列（三字母缩写）
|
{VAL}{LEU}{GLY}{LYS}{LEU}{SER}{GLN}{GLU}{LEU}{HIS}{LYS}{LEU}{GLN}{THR}{TYR}{PRO}{ARG}{THR}{ASN}{THR}{GLY}{SER}{GLY}{THR}{PRO}-NH2
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| C-端
|
NH2
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| 基本描述
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Calcitonin is a hormone known to participate in calcium and phosphorus metabolism. In mammals, the major source of calcitonin is from the parafollicular or C cells in the thyroid gland. Calcitonin is a 32 amino acid peptide cleaved from a larger prohormone. It contains a single disulfide bond, which causes the amino terminus to assume the shape of a ring. Alternative splicing of the calcitonin pre-mRNA can yield a mRNA encoding calcitonin gene-related peptide; that peptide appears to function in the nervous and vascular systems.
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| 溶解度
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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| 分子量
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2725.080
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| 化学式
|
C119H198N36O37
|
| 纯度
|
> 95%
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| 存储条件
|
Store at -20°C. Keep tightly closed. Store in a cool dry place
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| 注释
|
Amylin receptor antagonist.
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| Documents
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| Figures
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| Reference
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Chigurupati S, Kulkarni T et al. Calcitonin stimulates multiple stages of angiogenesis by directly acting on endothelial cells. Cancer Res. Sep 2005;65(18):8519-29.
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Calcitonin (8-32), Salmon
