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产品  
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Endomorphin-2
| 名称
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Endomorphin-2
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| 别名
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Endomorphin2
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| 序列（单字母缩写）
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YPFF-NH2
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| 序列（三字母缩写）
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{TYR}{PRO}{PHE}{PHE}-NH2
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| C-端
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NH2
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| 基本描述
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Endomorphin 2 is a potent, selective endogenous µ opioid receptor agonist. The physiological function of endomorphin-2 as a neurotransmitter or neuromodulator may cease through the rapid enzymatic process in the synapse of brain, as for other neuropeptides. Some results indicate that the administration of the endogenous µ-opioid ligand endomorphin-2, but not endomorphin-1, into the brain produces an antitussive effect via mainly naloxonazine-insensitive µ-opioid receptors, namely µ2-opioid receptors and partially kappa-opioid receptors.
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| 溶解度
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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| 分子量
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571.670
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| 化学式
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C32H37N5O5
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| 纯度
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> 95%
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| 存储条件
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Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
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| 注释
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Store at -20°C. Keep tightly closed.
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| Documents
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| Figures
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| Reference
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Viard E and Sapru HN, et al. Endomorphin-2 in the medial NTS attenuates the responses to baroreflex activation. Brain Res. Feb 2006; 1073-1074:365-373.
Botros M, et al. Endomorphin-1 and endomorphin-2 differentially interact with specific binding sites for substance P (SP) aminoterminal SP(1-7) in the rat spinal cord. Peptides. Apr 2006; 27(4):753-759.
Mizoguchi H, et al. Possible Involvement of Dynorphin A-(1-17) Release via {micro}1-Opioid Receptors in Spinal Antinociception by Endomorphin-2. J. Pharmacol. Exp. Ther. Apr 2006; 317(1): 362-368.
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