|
服务
产品  
|
PACAP (1-27), Human, Ovine, Rat
| 名称
|
PACAP (1-27), Human, Ovine, Rat
|
| 别名
|
HIV-1 TAT Protein Peptide; HIV1 TAT Protein PeptideHIV-1 TAT; HIV1 TAT
|
| 序列（单字母缩写）
|
HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH2
|
| 序列（三字母缩写）
|
{HIS}{SER}{ASP}{GLY}{ILE}{PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}-NH2
|
| C-端
|
NH2
|
| 基本描述
|
PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats. PACAP (1-27) shows considerable homology with Vasoactive Intestinal Polypeptide (VIP), and can stimulate adenylate cyclase much more potently than VIP. The PACAP(1-27)-induced increase in pancreatic venous blood flow was blocked by PACAP(6-27) but not by atropine. Therefore, the endocrine secretagogue effect of PACAP(1-27) is primarily mediated by the PAC(1) receptor, and that PACAP(1-27) may interact with muscarinic receptor function in PACAP-induced insulin and glucagon secretion in the canine pancreas in vivo.
|
| 分子量
|
3147.620
|
| 化学式
|
C142H224N40O39S1
|
| 纯度
|
> 95%
|
| 存储条件
|
Store at -20°C.
|
| 注释
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
|
|
