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服务
产品  
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Β-Melanocyte Stimulating Hormone (MSH), Human
| 名称
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Β-Melanocyte Stimulating Hormone (MSH), Human
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| 别名
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beta melanocyte stimulating hormoneβ-MSH, human
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| 序列（单字母缩写）
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AEKKDEGPYRMEHFRWGSPPKD
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| 序列（三字母缩写）
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{ALA}{GLU}{LYS}{LYS}{ASP}{GLU}{GLY}{PRO}{TYR}{ARG}{MET}{GLU}{HIS}{PHE}{ARG}{TRP}{GLY}{SER}{PRO}{PRO}{LYS}{ASP}
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| 基本描述
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Alpha-MSH (melanocyte stimulating hormone) has generally been assumed to be the endogenous ligand acting at the melanocortin-4 receptor (MC4-R), activation of which in the hypothalamus leads to reduced feeding. However, beta-MSH is also capable of activating MC4-R and inhibiting feeding. The researchers found that obese children are more likely to carry a rare variant of so-called beta-melanocyte-stimulating hormone (beta-MSH) than children of normal weight.
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| 分子量
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2661.000
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| 化学式
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C118H174N34O35S1
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| 纯度
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> 95%
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| 存储条件
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Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
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| 注释
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| Documents
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| Figures
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| Reference
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Spencer JD, et al. A novel mechanism in control of human pigmentation by {beta}-melanocyte-stimulating hormone and 7-tetrahydrobiopterin. J.Endocrinol. Nov 2005; 187(2): 293-302.
Leder EH, Silverstein JT. The pro-opiomelanocortin genes in rainbow trout (Oncorhynchus mykiss): duplications, splice variants, and differential expression. J.Endocrinol. Feb 2006; 188(2): 355-363.
Hinney A, et al. Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany. J.Clin.Endocrinol.Metab. May 2006; 91(5): 1761-1769.
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