| 名称
|
GLP-1/Glucagon-Like Peptide-1 (1-36) amide, human
|
| 编码
|
[99658-04-5]
|
| 别名
|
GLP-1/Glucagon-Like Peptide-1 (1-36) amide, human
|
| 纯度
|
80%,90%,95%,98%,99%
|
| 重量
|
1mg,5mg,10mg,50mg,100mg,1g
|
| 序列(单字母缩写)
|
HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2
|
| 序列(三字母缩写)
|
H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2?(trifluoroacetate salt)
|
| 基本描述
|
GLp-1 fragment that is isolated from the lower small intestine and is presently regarded to be the most important incretin hormone. It shows a strong insulinotropic effect that is mediated by receptors expressed in the pancreatic beta-cells. It is proposed to be a novel therapeutic strategy for non-insulin-dependent (type 2) diabetes mellitus and associated neuropathy.
|
| 溶解度
|
|
| 分子量
|
4111.5
|
| 化学式
|
C184H273N51O57
|
| 存储条件
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| 注释
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
G. Bell et al., Nature, 304, 368 (1983)
D.J.Drucker et al., Proc. Natl. Acad. Sci. USA, 84, 3434 (1987)
|
| C端
|
|
| N端
|
|
| 化学桥
|
|