| Name
|
Angiotensin I, Human
|
| Other Name
|
Hypertensin IAngiotensin I human acetate hydrate; renin angiotensin; angiotensin receptor
|
| Sequence (Single letter abbreviations)
|
DRVYIHPFHL
|
| Sequence（Three letter abbreviations）
|
{ASP}{ARG}{VAL}{TYR}{ILE}{HIS}{PRO}{PHE}{HIS}{LEU}
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| Basic description
|
Angiotensin I is a putative neurotransmitter. Angiotensin I is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.
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| Solubility
|
The peptide is soluble in water (10 mg/ml), clear, and colorless.
|
| The molecular weight
|
1296.480
|
| Chemical formula
|
C62H89N17O14
|
| The purity
|
> 95%
|
| Storage conditions
|
Store the peptide at -20°C. Keep container tightly closed.
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| Annotation
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| Documents
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| Figures
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| Reference
|
Stanisavljevic S, et al. Angiotensin I-converting enzyme inhibitors block protein kinase C epsilon by activating bradykinin B1 receptors in human endothelial cells. J. Pharmacol. Exp. Ther. Mar 2006; 316(3): 1153-1158.
Corradi HR, et al. Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design. J. Mol. Biol. Mar 2006; 357(3): 964-974.
Nikolaeva MA, et al. Testicular isoform of angiotensin I-converting enzyme (ACE, CD143) on the surface of human spermatozoa: revelation and quantification using monoclonal antibodies. Am. J. Reprod. Immunol. Jan 2006; 55(1): 54-68.
Ahmad S., et al. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS One. 2011 Dec;6(12):e28501.
Ahmad S., et al. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS One. 2011 Jan;6(1):e15759.
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Angiotensin I, Human
