| Name
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Bradykinin
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| Other Name
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| Sequence (Single letter abbreviations)
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RPPGFSPFR
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| Sequence（Three letter abbreviations）
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{ARG}{PRO}{PRO}{GLY}{PHE}{SER}{PRO}{PHE}{ARG}
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| Basic description
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Bradykinin is an activate pain receptors. Bradykinin induces smooth muscle contraction; activates Ca2+-dependent nitric oxide synthetase. Bradykinin can also increase capillary permeability. Bradykinin is a potent stimulator of nitric oxide formation by vascular endothelium. Bradykinin also stimulates prostacyclin formation.
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| Solubility
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The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
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| The molecular weight
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1060.200
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| Chemical formula
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50H73N15O11
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| The purity
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> 95%
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| Storage conditions
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Store the peptide at -20°C. Keep container tightly closed.
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| Annotation
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| Documents
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| Figures
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| Reference
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Huang Z, et al. Modulation by bradykinin of angiotensin type 1 receptor-evoked RhoA activation of connective tissue growth factor expression in human lung fibroblasts. Am. J. Physiol. Lung Cell Mol. Physiol. Jun 2006; 290(6): L1291-L1299.
Tang HB, et al. Substance P release evoked by capsaicin or potassium from rat cultured dorsal root ganglion neurons is conversely modulated with bradykinin. J. Neurochem. Jun 2006; 97(5): 1412-1418.
Bromee T, et al. Uneven evolutionary rates of bradykinin B1 and B2 receptors in vertebrate lineages. Gene. May 2006; 373: 100-108.
Xi X., et al. Medusins: A new class of antimicrobial peptides from the skin secretions of phyllomedusine frogs. Biochimie. 2013 Jun;95(6):1288 - 96.
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Bradykinin
