| Name
|
CREBtide
|
| Other Name
|
|
| Sequence (Single letter abbreviations)
|
KRREILSRRPSYR
|
| Sequence（Three letter abbreviations）
|
{LYS}{ARG}{ARG}{GLU}{ILE}{LEU}{SER}{ARG}{ARG}{PRO}{SER}{TYR}{ARG}
|
| Basic description
|
CREBtide is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein). The rate of CREBtide phosphorylation was at least as great as that of delta-CREB, indicating that CREBtide retained the determinants of delta-CREB which were responsible for substrate efficacy.
|
| Solubility
|
Soluble in water
|
| The molecular weight
|
1717.000
|
| Chemical formula
|
C73H129N29O19
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
Peptide corresponding to the consensus phosphorylation site at Ser133 of the cyclic AMP response element binding protein (CREB).
|
| Documents
|
|
| Figures
|
|
| Reference
|
|
CREBtide
