| Name
|
HIF-1 Alpha (556-574)
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| Other Name
|
HIF-1 alpha (556-574)
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| Sequence (Single letter abbreviations)
|
DLDLEMLAPYIPMDDDFQL
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| Sequence（Three letter abbreviations）
|
{Asp}{Leu}{Asp}{Leu}{Glu}{Met}{Leu}{Ala}{Pro}{Tyr}{Ile}{Pro}{Met}{Asp}{Asp}{Asp}{Phe}{Gln}{Leu}
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| Basic description
|
This is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely vital to the binding process.
|
| The molecular weight
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2254.600
|
| Chemical formula
|
C101H152N20O34S2
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
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| Documents
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| Figures
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| Reference
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HIF-1 Alpha (556-574)
