| Name
|
Handle Region Peptide (HRP),Rat
|
| Other Name
|
HA (126-138)
|
| Sequence (Single letter abbreviations)
|
RILLKKMPSV
|
| Sequence（Three letter abbreviations）
|
{Arg}{Ile}{Leu}{Leu}{Lys}{Lys}{Met}{Pro}{Ser}{Val}
|
| Basic description
|
A decoy receptor, or sink receptor, is a receptor that binds a ligand, inhibiting it from binding to its normal receptor. For instance, the receptor VEGFR-1 can prevent vascular endothelial growth factor (VEGF) from binding to the VEGFR-2.When a prorenin-binding protein interacts with the “handle” region of the prorenin prosegment, the prorenin molecule undergoes a conformational change to an enzymatically active state (5). This phenomenon is called nonproteolytic activation.
|
| The molecular weight
|
1184.540
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
Curr Hypertens Rep. 2008 Oct;10(5):405-9,Author:Müller DN.
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Handle Region Peptide (HRP),Rat
