| Name
|
IKKγ NBD Inhibitory Peptide
|
| Other Name
|
IKKγ NBD Inhibitory Peptide
|
| Sequence (Single letter abbreviations)
|
DRQIKIWFQNRRMKWKKTALDWSWLQTE
|
| Sequence(Three letter abbreviations)
|
{Asp}{Arg}{Gln}{Ile}{Lys}{Ile}{Trp}{Phe}{Gln}{Asn}{Arg}{Arg}{Met}{Lys}{Trp}{Lys}{Lys}{Thr}{Ala}{Leu}{Asp}{Trp}{Ser}{Trp}{Leu}{Gln}{Thr}{Glu}
|
| Basic description
|
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
|
| The molecular weight
|
3693.300
|
| Chemical formula
|
C170H259N49O42S1
|
| The purity
|
> 95%
|
| Storage conditions
|
Stored at -20°C. Keep tightly closed.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
|