| Name
|
Jagged-1 (188-204)
|
| Other Name
|
|
| Sequence (Single letter abbreviations)
|
CDDYYYGFGCNKFCRPR
|
| Sequence（Three letter abbreviations）
|
{Cys}{Asp}{Asp}{Tyr}{Tyr}{Tyr}{Gly}{Phe}{Gly}{Cys}{Asn}{Lys}{Phe}{Cys}{Arg}{Pro}{Arg}
|
| Basic description
|
This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the more conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-αB activation.
|
| The molecular weight
|
2107.400
|
| Chemical formula
|
C93H124N25O26S3
|
| The purity
|
> 95%
|
| Storage conditions
|
Store the peptide at -20°C.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
|
Jagged-1 (188-204)
