| Name
|
Neuropeptide Y, Human
|
| Other Name
|
NPY
|
| Sequence (Single letter abbreviations)
|
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2
|
| Sequence（Three letter abbreviations）
|
{TYR}{PRO}{SER}{LYS}{PRO}{ASP}{ASN}{PRO}{GLY}{GLU}{ASP}{ALA}{PRO}{ALA}{GLU}{ASP}{MET}{ALA}{ARG}{TYR}{TYR}{SER}{ALA}{LEU}{ARG}{HIS}{TYR}{ILE}{ASN}{LEU}{ILE}{THR}{ARG}{GLN}{ARG}{TYR}-NH2
|
| C-port
|
NH2
|
| Basic description
|
Neuropeptide Y (NPY) is a vasoconstrictor and a brain peptide that inhibits Ca2+-activated K+ channels in vascular smooth muscle. Neuropeptide Y (NPY) is implicated in the control of blood pressure, sexual behavior, and food intake. Neuropeptide Y (NPY) inhibits cholecystokinin- and secretin-stimulated pancreatic secretion.
|
| Solubility
|
Solvent: 1 mg/ml CH3COOH 0.05 M clear, colorless
|
| The molecular weight
|
4271.680
|
| Chemical formula
|
C189H285N55O57S1
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
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| Documents
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| Figures
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| Reference
|
Thiriet N, et al. Neuropeptide Y protects against methamphetamine-induced neuronal apoptosis in the mouse striatum. J. Neurosci. Jun 2005; 25(22): 5273-5279.
Bromee T, et al. Neuropeptide Y-family receptors Y and Y in chicken. Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region. FEBS. J. May 2006; 273(9): 2048-2063.
Amlal H, et al. Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line. Cancer Res. Apr 2006; 66(7): 3706-3714.
|
Neuropeptide Y, Human
