| Name
|
[Sar1, Ile8]-Angiotensin II
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| Other Name
|
AngiotensinII; Angiotensin 2; Angiotensin2
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| Sequence (Single letter abbreviations)
|
Sar-RVYIHPI
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| Sequence（Three letter abbreviations）
|
{SAR}{ARG}{VAL}{TYR}{ILE}{HIS}{PRO}{ILE}
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| Basic description
|
The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. Our investigations found that the more potent competitive antagonist of angiotensin II-stimulated aldosterone production was the [Sar1, Ile8] derivative of angiotensin II. However, this peptide was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin II on dog adrenal cells, and never reduced aldosterone production to basal levels.
|
| The molecular weight
|
968.150
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| Chemical formula
|
C46H73N13O10
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| The purity
|
> 95%
|
| Storage conditions
|
Storage at -20°C. Keep tightly closed.
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| Annotation
|
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| Documents
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| Figures
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| Reference
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[Sar1, Ile8]-Angiotensin II
