目录多肽

名称 Histrelin
编码 [220810-26-4]
别名 Histrelin
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Pyr-HWSYh(Bzl)-LRP-NHEt
序列（三字母缩写） Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-Leu-Arg-Pro-NHEt (acetate salt)
基本描述 Buserelin is a longer acting synthetic peptide analog of the naturally occurring gonadotropin-releasing hormone (GnRH/LHRH). Substitution of glycine in position 6 by D-serine and that of glycinamide in position 10 by ethylamide, leads to a nonapeptide with a significantly enhanced LHRH effect. The effects of buserelin on follicle-stimulating hormone (FSH) and luteinizing hormone (LH) release are approximately 20 to 170 times higher than those of natural LHRH.
溶解度
分子量 1323.52
化学式 C66H86N18O12
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Reference K.Sundaram et al., Life Sci., 28, 83 (1981) J.DeFazio et al., Endocr. Res., 10, 163 (1984) M.J.Gibson and D.S.Kohtz, Contraception, 31, 91 (1985) M.J.Karten and J.E.Rivier, Endocr. Rev., 7, 44 (1986) G.C.Doelle et al., Horm. Metab. Res., 18, 201 (1986) J.W.Gunnet et al., J. Endocrinol., 131, 211 (1991) M.Montagner et al., Reprod. Fertil. Dev., 17, 222 (2005) Merck Index, 14th ed., No. 4722, (2006) E.D.Deeks, Drugs, 70, 623 (2010) N.Shore et al., BJU Int., 109, 226 (2012)
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