Name
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[Lys(Me2)372]-p53 (368-393), p53 K372(Me2), biotin-labeled, human
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Code
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The alias
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[Lys(Me2)372]-p53 (368-393), p53 K372(Me2), biotin-labeled, human
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Sequence (single letter abbreviation)
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Biotin-KGGHLKS-K(Me2)-KGQSTSRHKKLMFKTEGPDSD-NH2
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Sequence (three-letter abbreviation)
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Biotin-Lys-Gly-Gly-His-Leu-Lys-Ser-Lys(Me2)-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2(trifluoroacetate salt)
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A basic description
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p53K382Me2 is derived from amino acid residues 377-387 of human p53 tumor suppressor protein, with dimethylation at Lys382. DNA damage induces increased levels of this peptide, which is recognized by p53-binding protein 1 (53BP1). 53BP1 interacts with p53 and modulates its transactivation.
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solubility
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The molecular weight
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3467
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Chemical formula
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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Huang, J. et al. Nature 440, 629 (2006)
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The C-terminal
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The N-terminal
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Chemical bridge
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