Name
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[Lys(Me3)382]-p53 (377-387); p53K382Me3
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Code
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The alias
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[Lys(Me3)382]-p53 (377-387); p53K382Me3
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Sequence (single letter abbreviation)
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TSRHK-K(Me3)-LMFKT
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Sequence (three-letter abbreviation)
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H-Thr-Ser-Arg-His-Lys-Lys(Me3)-Leu-Met-Phe-Lys-Thr-OH (trifluoroacetate salt)
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A basic description
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This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development.
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solubility
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The molecular weight
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1418.7
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Chemical formula
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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irskaia, I. et al. J Biol Chem 283, 34660 (2008)
Shi, X. et al. Mol Cell 27, 636 (2007)
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The C-terminal
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The N-terminal
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Chemical bridge
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