Catalog peptides

Name [Lys(Me3)382]-p53 (377-387); p53K382Me3
Code
The alias [Lys(Me3)382]-p53 (377-387); p53K382Me3
Sequence (single letter abbreviation) TSRHK-K(Me3)-LMFKT
Sequence (three-letter abbreviation) H-Thr-Ser-Arg-His-Lys-Lys(Me3)-Leu-Met-Phe-Lys-Thr-OH (trifluoroacetate salt)
A basic description This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development.
solubility
The molecular weight 1418.7
Chemical formula
The purity 80%,90%,95%,98%,99%
Weight 1mg,5mg,10mg,50mg,100mg,1g
Storage conditions Store at -20°C. Keep tightly closed. Store in a cool dry place.
Annotation
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Reference irskaia, I. et al. J Biol Chem 283, 34660 (2008) Shi, X. et al. Mol Cell 27, 636 (2007)
The C-terminal
The N-terminal
Chemical bridge

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