Name
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[Phe1,Ser2,Tyr6]-Protease Activated Receptor-1 (1-6) amide, human
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Code
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[245329-02-6]
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The alias
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[Phe1,Ser2,Tyr6]-Protease Activated Receptor-1 (1-6) amide, human
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Sequence (single letter abbreviation)
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FSLLRY-NH2
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Sequence (three-letter abbreviation)
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H-Phe-Ser-Leu-Leu-Arg-Tyr-NH2?(trifluoroacetate salt)
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A basic description
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This peptide is the tethered ligand sequence of mouse PAR-2, which like the thrombin receptor is a protease-activated receptor present in keratinocytes. This peptide was found to be equipotent with SFLLRN in activating keratinocyte inositolphospholipid hydrolysis and calcium mobilization.
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solubility
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The molecular weight
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796.97
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Chemical formula
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C39H60N10O8
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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B.Al-Ani et al., J. Pharmacol. Exp. Ther., 300, 702 (2002)
S.Wilson et al., Biochem. J., 388, 967 (2005)
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The C-terminal
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The N-terminal
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Chemical bridge
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