Name
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TRAP-14
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Code
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[137339-65-2]
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The alias
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TRAP-14
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Sequence (single letter abbreviation)
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SFLLRNPNDKYEPF
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Sequence (three-letter abbreviation)
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H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH (trifluoroacetate salt)
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A basic description
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This peptide can inhibit monocyte spreading on fibronectin-coated slides. The rapidly induced withdrawal of pseudopodial processes and rounding of the cells is accompanied by nitric oxide and endothelin-1 release. Spreading might be inhibited by autocrine endothelin-1 release and subsequent endothelin B receptor-dependent nitric oxide production
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solubility
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The molecular weight
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1739.95
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Chemical formula
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C81H118N20O23
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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T.-K.H.Vu et al., Cell, 64, 1057 (1991)
Y.Maruyama et al., Biochem. Biophys. Res. Commun., 199, 1262 (1994)
Duhamel-Clérin, E. et al. Arterioscler. Thromb. Vasc. Biol. 17, 1931 (1997)
Vassallo, R. et al. J. Biol. Chem. 267, 6081 (1992)
Y. Sugama and AB. Malik. Circ. Res. 71, 1015 (1992)
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The C-terminal
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The N-terminal
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Chemical bridge
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