| Name
|
α-Defensin 6
|
| Code
|
|
| The alias
|
α-Defensin 6
|
| Sequence (single letter abbreviation)
|
AFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL(Cys4 and Cys31/Cys6 and Cys20/Cys10 and Cys30 Bridge)
|
| Sequence (three-letter abbreviation)
|
Ala-Phe-Thr-Cys-His-Cys-Arg-Arg-Ser-Cys-Tyr-Ser-Thr-Glu-Tyr-Ser-Tyr-Gly-Thr-Cys-Thr-Val-Met-Gly-Ile-Asn-His-Arg-Phe-Cys-Cys-Leu(Cys4 and Cys31/Cys6 and Cys20/Cys10 and Cys30 Bridge)
|
| A basic description
|
Carbocalcitonin, the amino-suberic acid analog of eel calcitonin, has all the biological properties of the corresponding natural calcitonin. ?The substitution of the disulfide bond of natural calcitonins with an ethylene bridge in the 1-7 N-terminal position gives elcatonin greater stability and excellent tolerability when used in vivo.
|
| solubility
|
|
| The molecular weight
|
3708.27
|
| Chemical formula
|
C156H228N46O46S7
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
Z.Wu et al., J. Pept. Res., 64, 118 (2004) M.J.Nam et al., J. Biol. Chem., 280, 8260 (2005) E.Hazrati et al., J. Immunol., 177, 8658 (2006) A.Szyk et al., Protein Sci., 15, 2749 (2006) M.E.Klotman et al., J. Immunol., 180, 6176 (2008)
|
| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
(Cys4 and Cys31/Cys6 and Cys20/Cys10 and Cys30 Bridge)
|