Name
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Tamra-β-Amyloid (1-28)|Tamra-beta-Amyloid (1-28)
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Code
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[109770-29-8]
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The alias
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Tamra-β-Amyloid (1-28)|Tamra-beta-Amyloid (1-28)
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Sequence (single letter abbreviation)
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Tamra-DAEFRHDSGYEVHHQKLVFFAEDVGSNK
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Sequence (three-letter abbreviation)
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Tamra-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH (trifluoroacetate salt)
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A basic description
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Cyclized peptide that binds strongly to heparin and inhibits binding of 125 I-labeled APP to heparin (IC50= 10-7M). It also blocks the heparin sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
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solubility
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The molecular weight
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3676
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Chemical formula
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C170H230N43O50
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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J. Kang et al., Nature, 325, 773 (1987)
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The C-terminal
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The N-terminal
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Chemical bridge
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