Name
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Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg
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Code
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[310427-94-2]
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The alias
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Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg
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Sequence (single letter abbreviation)
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R-E(EDANS)-EVNLDAEF-K(DABCYL)-R
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Sequence (three-letter abbreviation)
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H-Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(DABCYL)-Arg (trifluoroacetate salt)
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A basic description
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beta-Secretase Substrate II used for assaying beta-secretase activity and corresponds to the 'Swedish' Lys-Met/Asn-Leu mutation of amyloid precursor protein (APP) beta-secretase cleavage site.
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solubility
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The molecular weight
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2005.2
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Chemical formula
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C91H129N25O25S1
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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A.K. Ghosh et al., J. Amer. Chem. Soc., 122, 3522 (2000)
J. Ermolieff et al., Biochemistry, 39, 12450 (2000)
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The C-terminal
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The N-terminal
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Chemical bridge
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