| Name
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(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676)
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| Code
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[186142-28-9]
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| The alias
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(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676)
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| Sequence (single letter abbreviation)
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SEVNLDAEFR
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| Sequence (three-letter abbreviation)
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H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-OH (trifluoroacetate salt)
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| A basic description
|
Peptide substrate that corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer's disease, henceforth referred to as the "Swedish "mutation. The peptide has been used for assaying cleavage at leucine-aspartate by cathespin G and chymotrypsin, whereas neither cathepsin B, D, nor L generated any products.
|
| solubility
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|
| The molecular weight
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0
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| Chemical formula
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C50H78N14O19
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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F. Grüninger-Leitch, et al., Nat. Biotechnol. 18, 66 (2000)
S. Sinha, et al., Nature 402, 537 (1999)
R. Vasser, et al., Science 286, 735 (1999)
R. Yan, et al., Nature 402, 533 (1999)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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