Name
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(Val671)-Amyloid b/A4 Protein Precursor770 (667-676)
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Code
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[252256-43-2]
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The alias
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(Val671)-Amyloid b/A4 Protein Precursor770 (667-676)
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Sequence (single letter abbreviation)
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SEVKVDAEFR
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Sequence (three-letter abbreviation)
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H-Ser-Glu-Val-Lys-Val-Asp-Ala-Glu-Phe-Arg-OH (trifluoroacetate salt)
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A basic description
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Inhibitor of gamma-secretase, a protease, and believed to aid in the prevention of Alzheimer's disease. It additionally cleaves the amyloid precursor protein (APP), a enzyme.
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solubility
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The molecular weight
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1179.3
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Chemical formula
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C51H82N14O18
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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M. Citron et al., Neuron, 14, 661 (1995)
R. Vasser et al., Science, 286, 735 (1999)
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The C-terminal
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The N-terminal
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Chemical bridge
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