| Name
|
Z-Leu-Leu-Nle-CHO
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| Code
|
|
| The alias
|
Z-Leu-Leu-Nle-CHO
|
| Sequence (single letter abbreviation)
|
Z-LL-Nle-CHO
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| Sequence (three-letter abbreviation)
|
Z-Leu-Leu-Nle-CHO
|
| A basic description
|
Novel polypeptide that suppresses neuronal cell death induced by several familial Alzheimer's disease genes and by amyloid beta-protein (human). The secretion of amyloid beta-protein (1-40) and amyloid beta protein (1-42) has been shown not to be affected by humanin in F11 cells expressing the familial Alzheimer's disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid beta-protein have been suggested.
|
| solubility
|
|
| The molecular weight
|
475.6
|
| Chemical formula
|
C26H41N3O5
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
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|
| Documents
|
|
| Figures
|
|
| Reference
|
T. Hartmann et al., Nature Med., 3, 1016 (1997)
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| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
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