Name
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Enfuvirtide; T-20
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Code
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[159519-65-0]
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The alias
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Enfuvirtide; T-20
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Sequence (single letter abbreviation)
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Ac-YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF-NH2
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Sequence (three-letter abbreviation)
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Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2?(trifluoroacetate salt)
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A basic description
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Virus replication inhibitory peptide a potent specific inhibitor of the replication of paramyxovirus and myxovirus, by inhibiting the membrane fusing activity of a viral glycoprotein.
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solubility
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The molecular weight
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4491.94
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Chemical formula
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C204H301N51O64
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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H.B.Fung and Y.Guo, Clin. Ther., 26, 352 (2004)
R.Manfredi and S.Sabbatani, Curr. Med. Chem., 13, 2369 (2006)
J.Ruof et al., Clin. Drug Investig., 27, 469 (2007)
A.Streinu-Cercel et al., HIV Clin. Trials, 9, 375 (2008)
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The C-terminal
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The N-terminal
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Chemical bridge
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