| Name
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Ac-N-Me-Tyr-Val-Ala-Asp-CHO
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| Code
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[160806-26-8]
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| The alias
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Ac-N-Me-Tyr-Val-Ala-Asp-CHO
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| Sequence (single letter abbreviation)
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Ac-(NMe)Tyr-Val-Ala-Asp-CHO
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| Sequence (three-letter abbreviation)
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Ac-(NMe)Tyr-Val-Ala-Asp-CHO
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| A basic description
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With a Kcat/Km of 3.3 x 106?M-1s-1?this fluorogenic caspase-1 substrate is cleaved 50-fold more efficiently than CASP-010. This phenomena shows that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.
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| solubility
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|
| The molecular weight
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506.6
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| Chemical formula
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C24H34N4O8
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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M.D.Mullican et al., Bioorg. Med. Chem. Letters, 4, 2359 (1994)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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