| Name
|
Ac-Trp-Glu-His-Asp-AMC
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| Code
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[189275-74-9]
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| The alias
|
Ac-Trp-Glu-His-Asp-AMC
|
| Sequence (single letter abbreviation)
|
Ac-WEHD-AMC
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| Sequence (three-letter abbreviation)
|
Ac-Trp-Glu-His-Asp-AMC
|
| A basic description
|
Very potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.
|
| solubility
|
|
| The molecular weight
|
0
|
| Chemical formula
|
C38H40N8O11
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
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1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
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| Documents
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|
| Figures
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| Reference
|
T.A. Rano et al., Chem. Biol. 4, 149 (1997)
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| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
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