| Name
|
Ac-YVAD-CHO
|
| Code
|
[143313-51-3]
|
| The alias
|
Ac-YVAD-CHO
|
| Sequence (single letter abbreviation)
|
Ac-YVAD-CHO
|
| Sequence (three-letter abbreviation)
|
Ac-Tyr-Val-Ala-Asp-CHO
|
| A basic description
|
Irreversible inhibitor of caspase-1 (ICE) that has also been shown to be a potent therapeutic agent against in vivo liver apoptosis in mice
|
| solubility
|
|
| The molecular weight
|
492.5
|
| Chemical formula
|
C23H32N4O8
|
| The purity
|
80%,90%,95%,98%,99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
N.A. Thornberry et al., Nature 356, 768 (1992)
S.M. Molineaux et al., Proc. Natl. Acad. Sci. USA, 90, 1809 (1993)
N.P.C. Walker et al., Cell, 78, 343 (1994)
|
| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
|