Name
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Z-Val-Ala-Asp-AMC
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Code
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[219137-91-4]
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The alias
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Z-Val-Ala-Asp-AMC
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Sequence (single letter abbreviation)
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Z-VAD-AMC
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Sequence (three-letter abbreviation)
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Z-Val-Ala-Asp-AMC
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A basic description
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Specific substrate for the determination of caspase-1 and caspase-1-like enzyme activities. Cleavage of this peptide substrate at the P1 Asp residue causes a continuous fluorescent assay, thus useful both in FACS and fluorescence microscopy experiments. Caspase-3 is only weakly active on this substrate.
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solubility
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The molecular weight
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594.6
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Chemical formula
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C30H34N4O9
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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S.A. Loddick et al., NeuroReport 7, 1465 (1996)
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The C-terminal
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The N-terminal
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Chemical bridge
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