| Name
|
T7 Peptide / Tumstatin (74-98), human
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| Code
|
|
| The alias
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T7 Peptide / Tumstatin (74-98), human
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| Sequence (single letter abbreviation)
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TMPFLFCNVNDVCNFASRNDYSYWL (C7&C13 bridge)
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| Sequence (three-letter abbreviation)
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H-Thr-Met-Pro-Phe-Leu-Phe-Cys-Asn-Val-Asn-Asp-Val-Cys-Asn-Phe-Ala-Ser-Arg-Asn-Asp-Tyr-Ser-Tyr-Trp-Leu-OH (trifluoroacetate salt)(Cys7 and 13 bridge)
|
| A basic description
|
Potent and cell permeable calpain I and II inhibitor that reduces capsaicin-mediated cell death in cultured dorsal root ganglionand. This peptide is additionally a gamma-secretase-inhibitor that reduces occurrence of apoptosis in H2O2 and A23187 treated PC12 cells.
|
| solubility
|
|
| The molecular weight
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3018.4
|
| Chemical formula
|
C137H189N33O39S3
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
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1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
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| Documents
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|
| Figures
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|
| Reference
|
Maeshima Y., et al., Science 295, 140-143 (2002)
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| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
(Cys7 and 13 bridge)
|