| Name
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Apamin
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| Code
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[24345-16-2]
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| The alias
|
Apamin
|
| Sequence (single letter abbreviation)
|
CNCKAPETALCARRCQQH-NH2?(Cys1&Cys11,Cys3&Cys15 Bridge)
|
| Sequence (three-letter abbreviation)
|
H-Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2?(trifluoroacetate salt)(Cys1 and Cys11,Cys3 and Cys15 Bridge)
|
| A basic description
|
Tetraddecapeptide that is originally isolated from amphibian skin and is biologically active in both the central nervous system and gastrointestinal tract. Bombina bombina and bombina variegata variegata, a potent stimulant of gastric acid secretion, is proposed to be strong biologically active in central nervous system, e.g. suppressing feeding in rats. Bombesin-like peptides have been biochemically characterized in rat brain.
|
| solubility
|
|
| The molecular weight
|
2027.37
|
| Chemical formula
|
C79H131N31O24
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
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| Figures
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|
| Reference
|
J.Van Rietschoten et al., Eur. J. Biochem., 56, 35 (1975)
M.Hugues et al., Proc. Natl. Acad. Sci. USA, 79, 1308 (1982)
|
| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
(Cys1 and Cys11,Cys3 and Cys15 Bridge)
|