| Name
|
Astressin
|
| Code
|
|
| The alias
|
Astressin
|
| Sequence (single letter abbreviation)
|
fHLLREVLE-Nle-ARAEQLAQ-cyclo(EAHK)NRKL-Nle-EII-NH2
|
| Sequence (three-letter abbreviation)
|
H-DPhe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-cyclo(Glu-Ala-His-Lys)-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2(trifluoroacetate salt)
|
| A basic description
|
CRF antagonist, lyophilized solid that acts as a potent antagonist to CRF receptors to block the behavioral and physiological responses to a stressor when administered in the CNS.
|
| solubility
|
|
| The molecular weight
|
3563.2
|
| Chemical formula
|
C161H269N49O42
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
V. Martinez et al., J. Pharmacol. Exp. Ther., 280(2), 754 (1997)
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| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
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