| Name
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Cetrorelix
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| Code
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[120287-85-6]
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| The alias
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Cetrorelix
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| Sequence (single letter abbreviation)
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Ac-D-2-Nal-4-chloro-D-F-beta-(3-pyridyl)-D-ASY-D-Cit-LRPa-NH2
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| Sequence (three-letter abbreviation)
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Ac-D-2-Nal-4-chloro-D-Phe-beta-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2?(acetate salt)
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| A basic description
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GHK possesses a high affinity for copper(II) ions, with which it spontaneously forms a complex (GHK-Cu). This growth-modulating plasma tripeptide, when added at nanomolar concentrations to a wide group of cultured systems, produces a disparate set of responses ranging from the stimulation of growth and differentiation to outright toxicity. It may function by facilitating copper uptake into cells. GHK-Cu accelerates wound healing. The palmitoylated peptide is marketed as a cosmetic ingredient under the trade name Biopeptide CL. CAS Number (net): 49557-75-7.Growth-modulating plasma tripeptide that produces a variety of responses ranging from the stimulation of growth and differentiation of outright toxicity when added at nanomolar concentrations to cultured systems. It also serves as a facilitator of copper uptake into cells, which can accelerate wound healing.
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| solubility
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| The molecular weight
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1431.06
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| Chemical formula
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C70H92Cl1N17O14
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| The purity
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80%,90%,95%,98%,99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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T.Reissmann et al., Hum. Reprod. Update, 6, 322 (2000)
G.Emons et al., Endocr. Relat. Cancer, 10, 291 (2003)
D.B.Shapiro and D.Mitchell-Leef, Minerva Ginecol., 55, 373 (2003)
C.Gründker et al., Eur. J. Endocrinol., 151, 141 (2004)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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