Name
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Thrombin Substrate III, Fluorogenic
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Code
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The alias
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Thrombin Substrate III, Fluorogenic
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Sequence (single letter abbreviation)
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Benzoyl-FVR-AMC
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Sequence (three-letter abbreviation)
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Benzoyl-Phe-Val-Arg-AMC (trifluoroacetate salt)
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A basic description
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A stromelysin-1 substrate, which is also hydrolyzed by two other matrix metalloproteinases, collagenase and gelatinase, and by the bacterial metalloproteinase thermolysin. The thiopeptolide Ac-PLA-psi[COS]Nva-W-amide mimics the MMP-3 cleavage site Leu-Ala-Nva-Trp
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solubility
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The molecular weight
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681.8
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Chemical formula
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C37H43N7O6
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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L. Svendsen, et al., Folia Haematol, 98, 446 (1972)
R. Lottenberg, et al., Meth. Enz., 80, 341 (1981)
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The C-terminal
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The N-terminal
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Chemical bridge
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