| Name
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Z-IETD-R110
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| Code
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| The alias
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Z-IETD-R110
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| Sequence (single letter abbreviation)
|
(Z-IETD)2-R110
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| Sequence (three-letter abbreviation)
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(Z-Ile-Glu-Thr-Asp)2-R110
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| A basic description
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This 14-mer prosaptide sequence is derived from the active neurotrophic region in the amino-terminal portion of the saposin C domain. Synthetic peptides derived from this region are biologically active and are named ?prosaptides.? Prosaposin and prosaptides are active on a variety of neuronal cells, stimulating sulfatide synthesis and increasing sulfatide concentration in Schwann cells and oligodendrocytes. This indicates that prosaposin and prosaptides are trophic factors for myelin formation.
|
| solubility
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|
| The molecular weight
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1515.6
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| Chemical formula
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C74H86N10O25
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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|
| Reference
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Science 281, 1312 (1998)
J Biol Chem 276, 6974 (2001)
Biochemistry 38, 13906 (1999)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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