Name
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DABCYL-TNF-a-EDANS (-4 to +6), human
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Code
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[396716-14-6]
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The alias
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DABCYL-TNF-a-EDANS (-4 to +6), human
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Sequence (single letter abbreviation)
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Dabcyl-LAQAVRSSSR-EDANS
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Sequence (three-letter abbreviation)
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DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS (trifluoroacetate salt)
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A basic description
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Synthesized substrate cleaved specifically at the Ala-Ser bond in order to liberate the C-terminal peptide-EDANS fragment from the proximity quenching effect of the DABCYL group, thus representing the first fluorescence-based assay of the herpes virus proteases and permits the characterization of potential inhibitors.
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solubility
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The molecular weight
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1573.8
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Chemical formula
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?C70H104N22O18S1
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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A.J. H.Gearing et al., Nature , 370, 555 (1994)
K.M. Mohler et al., Nature , 370, 218 (1994)
Becker BF, et al.Biol Chem 383, 1821-6 (2002)
Mohler KM, et al., Nature 370, 218-20. (1994)
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The C-terminal
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The N-terminal
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Chemical bridge
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