| Name
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Thyrotropin Releasing Hormone, TRH (Human)
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| Code
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[24305-27-9]
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| The alias
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Thyrotropin Releasing Hormone, TRH (Human)
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| Sequence (single letter abbreviation)
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Pyr-HP-NH2
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| Sequence (three-letter abbreviation)
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Pyr-His-Pro-NH2
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| A basic description
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Peptide that binds with high affinity to CRF receptor types 1, 2a & 2b, stimulates cAMP accumulation from cells transfected with those receptors, and acts in vitro to releaes ACTH from dispersed rat anterior pituitary cells. In using a genomic library, the human urocortin has been cloned and localized to human chromosome 2. It has also been discovered that both human and rat urocortin share 95% identity within the mature peptide region.
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| solubility
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| The molecular weight
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362.4
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| Chemical formula
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C16H22N6O4
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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Ohki, K. et al. Chem. Pharm. Bull. 45, 194 (1997)
Laakkonen, L. et al. Mol. Pharmacol. 49, 1092 (1996)
Scanes, C. et al. Acta Endocrinol. (Copenh) 97, 448 (1981).
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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