| Name
|
Cys-LL-37
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| Code
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|
| The alias
|
Cys-LL-37
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| Sequence (single letter abbreviation)
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CLLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
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| Sequence (three-letter abbreviation)
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H-Cys-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH (trifluoroacetate salt)
|
| A basic description
|
Like ω-conotoxin GVIA, this Conus magus peptide inhibits presynaptic Ca2+ channels. However, ω-conotoxin MVIIC clearly inhibits additional Ca2+ channel subtypes in the mammalian central nervous system.This Conus magus peptide inhibits multiple types of channels including N- and P-channels.
|
| solubility
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|
| The molecular weight
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4596.47
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| Chemical formula
|
C208H345N61O54S1
|
| The purity
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80%，90%，95%，98%，99%
|
| Weight
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1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
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| Documents
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|
| Figures
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|
| Reference
|
Schmidtchen A, Frick IM, Andersson E, Tapper H, Bj?rck L. 2002.
Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37. Mol Microbiol. 2002 46(1):157-168.
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| The C-terminal
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| The N-terminal
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|
| Chemical bridge
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