| Name
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Exendin-4
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| Code
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[141758-74-9]
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| The alias
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Exendin-4
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| Sequence (single letter abbreviation)
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HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
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| Sequence (three-letter abbreviation)
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H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2?(trifluoroacetate salt)
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| A basic description
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A new member of the Glucagon superfamily that was originally isolated from the venom of the lizard, Heloderma Horridum. At low concentrations, it interacts with putative exendin receptors causing an increase in pancreatic acinar cAMP, while at higher concentrations it interacts with VIP receptors to stimulate an increase in cellular cAMP and amylase release.
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| solubility
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| The molecular weight
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4186.7
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| Chemical formula
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C184H282N50O60S1
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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J. Eng et al., J. Biol. Chem., 267(11), 7402 (1992)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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